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Stroke-like migraine attacks after radiation therapy-also known as SMART syndrome-constitute a rare condition typically characterized by headache, seizures, vision abnormalities, hemiparesis, and aphasia. The condition usually resolves within a few days or weeks of onset with no residual impairments. However, resolution in some cases extends over a period of months rather than weeks and may be incomplete. The purpose of this case report is to provide an in-depth description of the progression of changes in cognitive and language functioning for a person exhibiting SMART syndrome characterized by slow recovery.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Language treatment | Behavioral | Individual speech-language therapy sessions totaling 1.5 to 2.5 hours five days per week. Intervention activities include performing oral and written confrontation and responsive naming, writing single words to dictation, reading single words and sentences aloud, and generating written and spoken picture descriptions. |
| Measure | Description | Time Frame |
|---|---|---|
| Standardized assessment | Aphasia Quotient of the Western Aphasia Battery - Revised | Change from baseline at 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Spoken picture description | Spoken language sample elicited through a request to describe events depicted in a Norman Rockwell drawing. | Change from baseline at 6 weeks, 10 weeks, 14 weeks, 20 weeks, and 26 weeks |
| Written picture description |
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Inclusion Criteria:
Exclusion Criteria:
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One adult with SMART syndrome will participate in this study. The person will have cognitive and language deficits typical of those exhibited by people with SMART syndrome. Given the rarity of the disorder, only one participant is anticipated.
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| Name | Affiliation | Role |
|---|---|---|
| Karen Hux, Ph.D. | Quality Living, Inc., Omaha, Nebraska | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Quality Living, Inc. | Omaha | Nebraska | 68104 | United States |
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| ID | Term |
|---|---|
| D008881 | Migraine Disorders |
| D001037 | Aphasia |
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D051270 | Headache Disorders, Primary |
| D020773 | Headache Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Written language sample elicited through a request to write about events depicted in a Norman Rockwell drawing.
| Change from baseline at 6 weeks, 10 weeks, 14 weeks, 20 weeks, and 26 weeks |
| D009422 | Nervous System Diseases |
| D013064 | Speech Disorders |
| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |