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| Name | Class |
|---|---|
| Chung-Ang University Hospital | OTHER |
| Kosin University Gospel Hospital | OTHER |
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This study was designed to evaluate the effectiveness of laparoscopic antireflux surgery for treatment of gastroesophageal reflux disease (GERD) comparing with that of non-surgical treatment.
To treat GERD, the most patients with GERD are managed with acid suppressive medication first, and followed by antireflux surgery when the medical therapy is not effective or when the patient prefer surgery to quit the medicine.
This study has a single cohort in which the patient has the past history of GERD and medical treatment with proton pump inhibitors, and has scheduled to have laparoscopic antireflux surgery for treatment of GERD.
Treatment outcome of surgery will be evaluated comparing with the outcome of medical treatment before registration.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Antireflux surgery following PPI | A single cohort with the GERD patients who had acid suppressive medication with proton pump inhibitor (PPI) followed by laparoscopic antireflux surgery |
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| Measure | Description | Time Frame |
|---|---|---|
| Symptom Control Rate of Surgical and Non-surgical Treatment for Gastroesophageal Reflux Disease (GERD) | GERD symptom control rate of surgical and non-surgical treatment for GERD based on the GERD symptom questionaire | Change from baseline GERD symptom at 3 months after antireflux surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Medical Cost of Surgical and Non-surgical Treatment for Gastroesophageal Reflux Disease (GERD) | Evaluation of medical cost based on public insurance system and patients' history | Change from baseline medical cost (non-surgical) at 3 months after antireflux surgery |
| Complication rate and adverse symptom rate related with antireflux surgery |
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Inclusion Criteria:
Exclusion Criteria:
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GERD patients who have history of PPI therapy and scheduled to undergo antireflux surgery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sungsoo Park, MD, PhD | Contact | +82-2-920-6772 | kugspss@korea.ac.kr | |
| Joongmin Park, MD, PhD | Contact | +82-2-6299-3124 | jmpark@cau.ac.kr |
| Name | Affiliation | Role |
|---|---|---|
| Sungsoo Park, MD, PhD | Korea University Anam Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Korea University Anam Hospital | Recruiting | Seoul | 02841 | South Korea |
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| ID | Term |
|---|---|
| D005764 | Gastroesophageal Reflux |
| ID | Term |
|---|---|
| D015154 | Esophageal Motility Disorders |
| D003680 | Deglutition Disorders |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
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Surgical complication and adverse symptom related with antireflux surgery evaluated with GERD symptom questionaire and case records |
| Change from baseline GERD symptom at 3 months after antireflux surgery |
| D004066 | Digestive System Diseases |