LSFG-SKIN, Laser Speckle Flowgraphy

LSFG-SKIN, Laser Speckle Flowgraphy

The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or environmental changes, such as temperature, light and pressure.

Laser speckle skin blood flow (LSFG-SKIN) will be recorded in normal subjects and in patients with disorders affecting skin capillary perfusion, which may include cardiovascular disorders, dermatologic disorders, skin wounds, ocular disorders, psychiatric disorders, and neurologic disorders.

Inclusion Criteria:

Controls

●Healthy normal control subjects ages 18-90

Cardiology Subjects

• Ages 18-90
• History of dysrhythmia, heart failure, cardiac ischemia, hypertension, peripheral vascular disease

Dermatology Subjects

• Ages 18-90
• History of inflammatory and cancerous lesions

Endocrine Subjects

• Ages 18-90
• History of diabetes, thyroid disease

Neurology Subjects

• Ages 18-90
• History of dementia, headaches, Parkinson's, light sensitivity, stroke, TIA, multiple sclerosis

Psychiatry Subjects

• Ages 18-90
• History of bipolar, schizophrenia, anxiety, depression

Surgery Subjects

• Ages 18-90
• History of skin wounds(trauma, chemotherapy, radiation), thermal burns, or plastic and reconstructive surgical procedures.

Ophthalmology Subjects

• Ages 18-90
• History of ocular disorders caused by hypo perfusion or inflammatory disorders

Exclusion Criteria:

Controls

• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma

Cardiology Subjects

• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.

• Angle closure glaucoma

  3. Dermatology Subjects

• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.

• Angle closure glaucoma

Endocrine Subjects

• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma

Neurology Subjects

• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma

Psychiatry Subjects

• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma

Surgery Subjects

• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma

Ophthalmology Subjects

• Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
• Angle closure glaucoma