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| Name | Class |
|---|---|
| Technical University of Denmark | OTHER |
| Herlev and Gentofte Hospital | OTHER |
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For patients admitted to the medical ward, it is often difficult to predict if their clinical condition will deteriorate, however subtle changes in vital signs are usually present 8 to 24 hours before a life-threatening event such as respiratory failure leading to ICU admission, or unanticipated cardiac arrest. Such adverse trends in clinical observations can be missed, misinterpreted or not appreciated as urgent. New continuous and wearable 24/7 clinical vital parameter monitoring systems offer a unique possibility to identify clinical deterioration before patients condition progress beyond the point-of-no-return, where adverse events are inevitable. The WARD-COPD project aims to determine the correlation between cardiopulmonary micro events and clinical adverse events during the first four days after hospital admission with acute exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD).
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Continuous monitoring system | Device | Patients recruited will be continuously monitored with Isansys Lifetouch patch, Isansys wireless blood pressure monitor, Nonin WristOx 3150, Empatica E4, and Radiometer TCM5 FLEX monitor. |
| Measure | Description | Time Frame |
|---|---|---|
| Any serious adverse events | E.g. cardiac arrest, ICU admission, acute myocardial infarction, stroke, sepsis, acute kidney injury or other serious adverse events (defined in Protocol Appendix A) | within 30 days after inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | within 6 months after inclusion | |
| Readmission | within 6 months after inclusion |
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Inclusion Criteria:
Exclusion Criteria:
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200 patients admitted to hospital with acute exacerbation of COPD will be included in the study upon arrival to the medical ward.
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| Name | Affiliation | Role |
|---|---|---|
| Christian Meyhoff, MD, PHD | Bispebjerg and Frederiksberg Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bispebjerg Hospital | Copenhagen | 2400 | Denmark | |||
| Gentofte Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35593967 | Derived | Elvekjaer M, Rasmussen SM, Gronbaek KK, Porsbjerg CM, Jensen JU, Haahr-Raunkjaer C, Molgaard J, Sogaard M, Sorensen HBD, Aasvang EK, Meyhoff CS. Clinical impact of vital sign abnormalities in patients admitted with acute exacerbation of chronic obstructive pulmonary disease: an observational study using continuous wireless monitoring. Intern Emerg Med. 2022 Sep;17(6):1689-1698. doi: 10.1007/s11739-022-02988-w. Epub 2022 May 20. |
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Troponin, Arterial Blood Gas
| Hellerup |
| 2900 |
| Denmark |
| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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