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This is a prospective, randomized controlled trial to evaluate the ability of hydrogen peroxide preparation in addition to chlorhexidine to decrease the colonization of Propionibacterium acnes(a bacteria commonly found in the dermis of the skin surrounding the shoulder in order to decrease postoperative joint infection.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| a. Standard iodine scrub, 3% hydrogen peroxide prep, follow by | Active Comparator |
| |
| b. Iodine scrub and ChloraPrep alone | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| a. Standard iodine scrub, 3% hydrogen peroxide prep, follow by ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcohol | Drug | a. Standard iodine scrub, 3% hydrogen peroxide prep, follow by ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcohol |
| Measure | Description | Time Frame |
|---|---|---|
| colonization of p.acnes in the dermis of the shoulder | number of colony forming units grown in bacterial culture | 14 days in culture |
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Inclusion Criteria:
1. All male patients (>18) undergoing shoulder arthroscopy
Exclusion Criteria:
Female patients
Patients with active acne
Patients who have taken antibiotics within a month of their surgery
Subjects allergic to any of the following agents:
o Benzoyl peroxide
Subjects with psoriatic/eczematous lesions on the shoulder girdle.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rothman Institute | Philadelphia | Pennsylvania | 19107 | United States |
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| Iodine scrub and ChloraPrep alone | Drug | Iodine scrub and ChloraPrep alone |
|
| ID | Term |
|---|---|
| C010882 | chlorhexidine gluconate |
| D019840 | 2-Propanol |
| ID | Term |
|---|---|
| D020005 | Propanols |
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
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