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The aim of the current study is to develop and validate an algorithm based on seismocardiography recordings to detect heart failure. Echocardiography will be used as the golden standard for defining patients with heart failure.
Seismocardiography is inspired from methods for the analysis of seismic activity and can be used to describe the heart's movements using a specially developed sensor placed on the patient's chest. The project aims to describe the motion of the heart using automated computer analysis of the seismocardiography signal for development of a simple method for the analysis of myocardial performance.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Seismocardiography | Device | Seismocardiography recording |
| Measure | Description | Time Frame |
|---|---|---|
| Area under the receiver-operator characteristic curve, sensitivity, specificity, and positive and negative predictive value of seismocardiography in detection of heart failure. | Heart failure defined as heart failure with reduced ejection fraction, heart failure with mid-range ejection fraction and heart failure with preserved ejection fraction combined. | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| Area under the receiver-operator characteristic curve, sensitivity, specificity, and positive and negative predictive value of seismocardiography and NT-proBNP, respectively, in detection of heart failure with reduced ejection fraction | 1 day | |
| Area under the receiver-operator characteristic curve, sensitivity, specificity, and positive and negative predictive value of seismocardiography in detection of heart failure with mid-range ejection fraction. |
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Inclusion Criteria:
Exclusion Criteria:
Extension study:
Inclusion criteria
Exclusion criteria
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Patients with clinically suspected heart failure
Extension study:
Patients with newly diagnosed HFrEF
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| Name | Affiliation | Role |
|---|---|---|
| Peter Søgaard, MD, DMSc | Aalborg University Hospital | Principal Investigator |
| Jacob Møller, MD, DMSc | Odense University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Aalborg University Hospital | Aalborg | 9000 | Denmark | |||
| Odense University Hospital |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| 1 day |
| Area under the receiver-operator characteristic curve, sensitivity, specificity, and positive and negative predictive value of seismocardiography in detection of heart failure with preserved ejection fraction. | 1 day |
| Adverse events related to the CADScor seismo device. | Count of adverse events | 1 day |
| Odense |
| 5000 |
| Denmark |