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Comparing the classical extracapsular tonsillectomy (TE) performed with electrosurgery to intracapsular approaches (SIPT) by coblation or microdebrider. The patient group is adults with recurrent or chronic tonsillitis
Extracapsular tonsillectomy (TE) with monopolar electrosurgery is the most commonly used approach in adult tonsil surgery in Turku University Central Hospital, Finland.
In our study setting we are comparing intracapsular tonsillectomy (subtotal/intracapsular/partial tonsillectomy (SIPT) ) as the intervention group with extracapsular tonsillectomy as the control group.
SIPT is done with either coblation or microdebrider and TE with monopolar electrosurgery.
Indications for surgery are recurrent tonsillitis or chronic tonsillitis. The patient group is adults (16-65 years)
Safety, efficiency and cost-effectiveness are monitored in a prospective, patient-blinded and randomised study setting.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ECTE/Electrosurgery | Active Comparator | Extracapsular tonsillectomy (ECTE) with monopolar electrosurgery |
|
| ICTE/Microdebrider | Experimental | Intracapsular tonsillectomy (ICTE) with microdebrider |
|
| ICTE/Coblator | Experimental | Intrapsular tonsillectomy (ICTE) with coblator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| tonsillectomy | Procedure | removal of tonsil tissue as described in the study arms |
|
| Measure | Description | Time Frame |
|---|---|---|
| Post-operative recovery | Pain post-operatively after discharge as self-reported pain intensity over the past day. Each day is scored with the modified Brief Pain Inventory and recovery is achieved when pain score reaches preset values. Recovery speed defined as pain VAS-score 3 or less at rest; or pain VAS-score 5 or less without regular analgesics use. Daily questionnaire used: Brief Pain Inventory. | 21 days |
| Measure | Description | Time Frame |
|---|---|---|
| Analgesics use | Need for analgesics postoperatively during 21 days. Measured as number of naprometin tablets/ day and the number of tramadol-paracetamol combination tablets/day. | 21 days |
| Post-operative bleeding |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jussi Jero, Professor | Turku University Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| TYKS Korvaklinikka | Turku | 20521 | Finland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36104143 | Background | Piitulainen JM, Uusitalo T, Sjoblom HM, Ivaska LE, Jegoroff H, Kauko T, Kokki H, Kyto E, Mansikka I, Ylikoski J, Jero J. Intracapsular tonsillectomy in the treatment of recurrent and chronic tonsillitis in adults: a protocol of a prospective, single-blinded, randomised study with a 5-year follow-up (the FINITE trial). BMJ Open. 2022 Sep 14;12(9):e062722. doi: 10.1136/bmjopen-2022-062722. | |
| 41954901 |
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All data relevant to the study are included in the article or uploaded as supplementary information.
Data will become available with the publication of the article
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| ID | Term |
|---|---|
| D014069 | Tonsillitis |
| D000084462 | Hyperthermia |
| ID | Term |
|---|---|
| D010612 | Pharyngitis |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D010608 | Pharyngeal Diseases |
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| ID | Term |
|---|---|
| D014068 | Tonsillectomy |
| ID | Term |
|---|---|
| D013517 | Otorhinolaryngologic Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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prospective, single-blinded, randomised, controlled
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Patients are masked with numbers and patient records not shown to the outcomes assessor
|
Bleeding post-operatively at the ward or at any point during 21 days. Measured as 1-4 (1= bleeding, stopped spontaneously, no contact with staff; 2: Contact with ER, bleeding stopped without intervention; 3: Bleeding, needed intervention (packing, topical adrenalin, electrosurgical hemostasis; 4: Needed OR-time, blood transfusion, ward days
| 21 days |
| Life Quality | Quality of life as defined by the questionnaires: Tonsillectomy Outcome Inventory 14 "TOI-14" preoperatively and 6 months after operation; | 6 months |
| Residual tonsil tissue | Residual tonsil measured right after surgery is completed and at 6 months follow-up. | 6 months |
| Revision surgery | The need of revision surgery after tonsillectomy, recorded with questionnaire: Nordic Tonsil Surgery Register | 5 years |
| Throat problems | Throat problems as described by the Nordic Tonsil Surgery Register at different time points postoperatively | 5 years |
| Life quality | Quality of life as defined by the questionnaires: Glasgow Benefit Inventory "GBI" at 6 months after operation. | 6 months |
| Derived |
| Uusitalo T, Sjoblom H, Ivaska LE, Kauko T, Kokki H, Mansikka I, Kyto E, Piitulainen J. Intracapsular vs Extracapsular Tonsillectomy Recovery Time: The FINITE Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2026 Jun 1;152(6):552-559. doi: 10.1001/jamaoto.2026.0284. |
| D009057 |
| Stomatognathic Diseases |
| D012140 | Respiratory Tract Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D001832 | Body Temperature Changes |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D018882 | Heat Stress Disorders |
| D014947 | Wounds and Injuries |