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The 50% effective concentration of remifentanil by target controlled infusion was not determined for inhibiting the haemodynamic response during double-lumen tube (DLT) intubation. Previous study showed that Airtraq videolaryngoscope provided more stable haemodynamics than Macintosh for double-lumen tube intubation. In this study, the investigators will compare the 50% effective concentration of remifentanil between Airtraq videolaryngoscope and Macintosh laryngoscope for inhibiting haemodynamic responses during DLT intubation.
Dixon "up-and-down" method was used to determine 50% effective concentration of remifentanil by target controlled infusion for inhibiting the haemodynamic responses during DLT intubation with Airtraq videolaryngoscope or Macintosh laryngoscope.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Airtraq | Experimental | Patients received DLT intubation by Airtraq videolarygoscope |
|
| Macintosh | Active Comparator | Patients received DLT intubation by Macintosh laryngoscope |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Airtraq | Device | Airtraq is a kind of videolaryngoscope for intubation |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Remifentanil TCI effect site concentration | preestablish remifentanil TCI effect site concentration(ng/ml) | through study completion, an average of 20 min |
| Measure | Description | Time Frame |
|---|---|---|
| mean arterial pressure | mean arterial pressure in mmHg | at entering the operation room(T1), at immediately before DLT intubation(T2), at immediately after DLT intubtion(T3), at 1 minute(T4)/2 minutes (T5)/3 minutes(T6) after DLT intubation |
| heart rate |
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Inclusion Criterias:
Exclusion Criterias:
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| Name | Affiliation | Role |
|---|---|---|
| Ailin Luo, M.D. | alluo@tjh.tjmu.edu.cn | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tongji Hospital, Huazhong University of Science and Technology | Wuhan | Hubei | 430030 | China |
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| Macintosh |
| Device |
Macintosh is a traditional laryngoscope for intubation |
|
heart rate in bpm |
| at entering the operation room(T1), at immediately before DLT intubation(T2), at immediately after DLT intubtion(T3), at 1 minute(T4)/2 minutes (T5)/3 minutes(T6) after DLT intubation |
| Narcotrend index | Narcotrend index in Arabic numerals | at entering the operation room(T1), at immediately before DLT intubation(T2), at immediately after DLT intubtion(T3), at 1 minute(T4)/2 minutes (T5)/3 minutes(T6) after DLT intubation |