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One-lung ventilation interrupts oxygenation. The effect of heated humidifed breathing circuit on arterial oxygenation during one-lung ventilation has not been investigated. The investigators will investigate the effect of the heated humidifed breathing circuit on oxygenation during one-lung ventilation in patients undergoing thoracoscopic surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Active Comparator | Heated breathing circuit will turned off. |
|
| Heat | Experimental | Heated breathing circuit will be turned on. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Heated and humidified breathing circuit on | Device | Heated and humidified breathing circuit will be turned on. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Arterial oxygenation | Arterial oxygenation (mmHg) will be measured by arterial blood analysis. | At 30 minutes after one-lung ventilation |
| Measure | Description | Time Frame |
|---|---|---|
| Arterial oxygenation | Arterial oxygenation (mmHg) will be measured by arterial blood analysis. | At 0, 15, 45, and 60 minutes after one-lung ventilation |
| Mean arterial pressure | Mean arterial pressure (mmHg) will be measured. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hyun-Chang Kim, MD Ph | Contact | +821028862876 | onidori1979@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Hyun-Chang Kim, MD PhD | Keimyung University | Principal Investigator |
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| Heated and humidified breathing circuit off | Device | Heated and humidified breathing circuit will be turned off. |
|
| At 0, 15, 30, 45, and 60 minutes after one-lung ventilation |
| Heart rate | Heart rate (beats/min) will be measured. | At 0, 15, 30, 45, and 60 minutes after one-lung ventilation |
| Temperature | Body temperature (°C) will be measured. | At 0, 15, 30, 45, and 60 minutes after one-lung ventilation |
| Central venous pressure | Mean central venous pressure (mmHg) will be measured by a central venous catheter. | At 0, 15, 30, 45, and 60 minutes after one-lung ventilation |
| Cardiac index | Cardiac index (l/min/m^2) will be measured by pulse-contour analysis. | At 0, 15, 30, 45, and 60 minutes after one-lung ventilation |
| Pressure peak | Peak pressure of ventilation (cmH2O) will be measured. | At 0, 15, 30, 45, and 60 minutes after one-lung ventilation |
| Pressure plateau | Plateau pressure of ventilation (cmH2O) will be measured. | At 0, 15, 30, 45, and 60 minutes after one-lung ventilation |
| Arterial carbon dioxide | Arterial carbon dioxide will be measured. | At 0, 15, 30, 45, and 60 minutes after one-lung ventilation |
| Arterial blood acidosis | Arterial blood acidosis will be measured. | At 0, 15, 30, 45, and 60 minutes after one-lung ventilation |
| Oxygen saturation of arterial blood | Oxygen saturation of arterial blood (%) will be measured. | At 0, 15, 30, 45, and 60 minutes after one-lung ventilation |