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The purpose of the study is to compare different short durations of radial clamp application following an angiogram via a trans-radial approach.
This is a single-center, prospective, randomized study that will enroll patients that are referred for an angiogram and will compare 3 different durations of radial clamp applications. Patients will be randomly assigned to either 10, 20 or 30-minute clamp applications. The clamps will be gradually released at the end of the assigned durations and participants will be assessed for the radial artery occlusion, hematoma, and other bleeding events.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 10 minutes | Experimental | Compression clamp release start after 10 minutes |
|
| 20 minutes | Experimental | Compression clamp release start after 20 minutes |
|
| 30 minutes | Active Comparator | Compression clamp release start after 30 minutes |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Compression clamp release | Other | Standard compression clamp is used and will be released at different times according to randomization |
|
| Measure | Description | Time Frame |
|---|---|---|
| Hematoma | Hematoma larger than 5 cm | 1 hour |
| Radial artery occlusion | Assessed by Doppler | 1 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Bleeding - any | Minor hematoma | 1 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison to prior study results | Compared to PRACTICAL study | 1 hour |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Shahar Lavi, MD | London Health Sceinces Centre | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| London Health Sciences Centre | London | Ontario | N6A5A5 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28159821 | Background | Lavi S, Cheema A, Yadegari A, Israeli Z, Levi Y, Wall S, Alemayehu M, Parviz Y, Murariu BD, McPherson T, Syed J, Bagur R. Randomized Trial of Compression Duration After Transradial Cardiac Catheterization and Intervention. J Am Heart Assoc. 2017 Feb 3;6(2):e005029. doi: 10.1161/JAHA.116.005029. |
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