Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of this study is to find out if one blood group phenotype is more responsive than the others to the nonsurgical periodontal treatment.
To the best of our knowledge, this is the first (research) randomized clinical trial that assesses how patient respond to the nonsurgical periodontal treatment based on their blood group phenotype.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients whose blood type is A | Applying nonsurgical periodontal treatment (scaling and root planning). |
| |
| Patients whose blood type is B | Applying nonsurgical periodontal treatment (scaling and root planning). |
| |
| Patients whose blood type is AB | Applying nonsurgical periodontal treatment (scaling and root planning). |
| |
| Patients whose blood type is O | Applying nonsurgical periodontal treatment (scaling and root planning). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| nonsurgical periodontal treatment | Procedure | patients will undergo nonsurgical periodontal treatment to reduce the relative attachment level and improve the probing depth. An initial session will be conducted to remove supra gingival plaque and calculus. another appointment is set to perform full moth scalling and root planing. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in relative attachment level. | the relative attachment level measures the length form the base of the periodontal pocket to a stent | measures will be taken at baseline and after two months from treatment. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in periodontal probing depth. | the distance between the gingival margin to the base of the periodontal pocket. | measures will be taken at baseline and after two months from treatment. |
| Change in gingival index |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Patients suffering from chronic periodontitis
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Mohammad Ammar Kouky, DDS MSc | PhD Student in Periododontics, University of Damascus Dental School, Damascus | Principal Investigator |
| Mohammad Monzer Alsabbagh, DDS MSc PhD | Associate Professor of Periodontics, University of Damascus Dental School, Damascus, Syria | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Periodontics | Damascus | DM20AM18 | Syria |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23493096 | Background | Pai GP, Dayakar MM, Shaila M, Dayakar A. Correlation between "ABO" blood group phenotypes and periodontal disease: Prevalence in south Kanara district, Karnataka state, India. J Indian Soc Periodontol. 2012 Oct;16(4):519-23. doi: 10.4103/0972-124X.106892. | |
| 19212557 | Background | Demir T, Tezel A, Orbak R, Eltas A, Kara C, Kavrut F. The Effect of ABO Blood Types on Periodontal Status. Eur J Dent. 2007 Jul;1(3):139-43. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D055113 | Chronic Periodontitis |
| ID | Term |
|---|---|
| D010518 | Periodontitis |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D016745 | Root Planing |
| ID | Term |
|---|---|
| D012534 | Dental Scaling |
| D003777 | Dental Prophylaxis |
| D010517 | Periodontics |
| D003813 | Dentistry |
Not provided
Not provided
Not provided
Not provided
Not provided
|
|
it is used to designate the level of the gingival inflammation.
| index will be taken at baseline and after two months from treatment. |
| Change in plaque Index | it is used to designate the level of plaque accumulation. | index will be taken at baseline and after two months from treatment. |
| 28839412 | Background | Gautam A, Mittal N, Singh TB, Srivastava R, Verma PK. Correlation of ABO Blood Group Phenotype and Rhesus Factor with Periodontal Disease: An Observational Study. Contemp Clin Dent. 2017 Apr-Jun;8(2):253-258. doi: 10.4103/ccd.ccd_307_17. |
| 26420728 | Background | Wang W, Liu L, Wang Z, Wei M, He Q, Ling T, Cao Z, Zhang Y, Wang Q, Shi M. Impact of ABO blood group on the prognosis of patients undergoing surgery for esophageal cancer. BMC Surg. 2015 Sep 29;15:106. doi: 10.1186/s12893-015-0094-1. |
| 27136434 | Background | Yu Q, Wang L, Zhang S, Feng T, Li L, Chen B, Chen M. The role of ABO blood groups in Crohn's disease and in monitoring response to infliximab treatment. Blood Transfus. 2016 Sep;14(5):460-4. doi: 10.2450/2016.0199-15. Epub 2016 Feb 24. |
| D002908 |
| Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D013357 |
| Subgingival Curettage |
| D011313 | Preventive Dentistry |