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| Name | Class |
|---|---|
| Medical University of Lublin | OTHER |
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The motivation results from the fact, that an intra-abdominal pressure is correlated with cerebral perfusion, in a mechanism of reducing venous outflow. Moreover, elevated intra-abdominal pressure leads to increase in intracranial pressure and decrease of cerebral perfusion pressure.
The main aim of the study was to investigate an influence of increase in intra-abdominal pressure on cerebral oxygenation measured with the use of non-invasive optical technique.
The investigators applied time resolved near infrared spectroscopy device in order to estimate changes in hemoglobin concentration in a brain during gynecological procedure that involves laparoscopy. The optodes were positioned on a forehead on left and right hemisphere.
The measurements were carried out during whole medical procedure, including anesthesia, start and stop of insufflation of abdominal cavity with carbon dioxide (CO2), surgical procedure, release of CO2 and waking up a patient. In those studies the special emphasis was put on a period of insufflation of abdominal cavity with CO2.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Laparoscopy | The group consists of patients who undergoes laparoscopy procedure during which changes in cerebral oxygenation are estimated. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Laparoscopy | Procedure | The studies are carried out on patients who undergoes gynecological procedure that involves laparoscopy. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Distribution of time of flight of photons | Distribution of time of flight of photons measured at 2 wavelengths, 690 nm and 830 nm and at 2 spots on a forehead | 90 minutes (typically) |
| Measure | Description | Time Frame |
|---|---|---|
| Cerebral oxygenation | Changes oxygenated (HbO2) and deoxygenated (Hb) hemoglobin concentrations expressed in micro Molars | 90 minutes (typically) |
| Fluctuations of changes in Hb and HbO2 concentrations |
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Inclusion Criteria:
Exclusion Criteria:
The studies are carried out on the gynecological ward of Medical University of Lublin what results in the fact that females were studied only.
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Patients of Gynecological Surgery Clinic
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| Name | Affiliation | Role |
|---|---|---|
| Adam Liebert, Prof | Nalecz Institute of Biocybernetics and Biomedical Engineering | Study Chair |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 8656480 | Background | Bloomfield GL, Ridings PC, Blocher CR, Marmarou A, Sugerman HJ. Effects of increased intra-abdominal pressure upon intracranial and cerebral perfusion pressure before and after volume expansion. J Trauma. 1996 Jun;40(6):936-41; discussion 941-3. doi: 10.1097/00005373-199606000-00012. | |
| 16193329 | Background | Deeren DH, Dits H, Malbrain ML. Correlation between intra-abdominal and intracranial pressure in nontraumatic brain injury. Intensive Care Med. 2005 Nov;31(11):1577-81. doi: 10.1007/s00134-005-2802-2. Epub 2005 Sep 29. |
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| ID | Term |
|---|---|
| D010535 | Laparoscopy |
| ID | Term |
|---|---|
| D004724 | Endoscopy |
| D003949 | Diagnostic Techniques, Surgical |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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Fourier transform of changes in concentrations of Hb and HbO2
| 90 minutes (typically) |
| 22352652 | Background | Kacprzak M, Liebert A, Staszkiewicz W, Gabrusiewicz A, Sawosz P, Madycki G, Maniewski R. Application of a time-resolved optical brain imager for monitoring cerebral oxygenation during carotid surgery. J Biomed Opt. 2012 Jan;17(1):016002. doi: 10.1117/1.JBO.17.1.016002. |
| D019060 | Minimally Invasive Surgical Procedures |
| D013514 | Surgical Procedures, Operative |