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To evaluate the safety and efficacy of CJ-30061 compared with amlodipine/valsartan combination therapy and valsartan/atorvastatin combination therapy in hypertensive patients with hyperlipidemia
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Test | Experimental | Amlodipine 10mg+Valsartan 160mg+Atorvastatin 40mg |
|
| Reference 1 | Active Comparator | Amlodipine 10mg+Valsartan 160mg |
|
| Reference 2 | Active Comparator | Valsartan 160mg+Atorvastatin 40mg |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Amlodipine 10mg+Valsartan 160mg+Atorvastatin 40mg | Drug | Amlodipine 10mg+Valsartan 160mg+Atorvastatin 40mg |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in siSBP | Change in siSBP from baseline after 8 weeks of study treatment | baseline and 8 weeks |
| Change in LDL-C | Change in LDL-C from baseline after 8 weeks of study treatment | baseline and 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Duk-Hyun Kang, Ph.D | Asan Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Asan Medical Center | Seoul | South Korea |
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| Amlodipine 10mg+Valsartan 160mg | Drug | Amlodipine 10mg+Valsartan 160mg |
|
| Valsartan 160mg+Atorvastatin 40mg | Drug | Valsartan 160mg+Atorvastatin 40mg |
|
| ID | Term |
|---|---|
| D006973 | Hypertension |
| D006949 | Hyperlipidemias |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D050171 | Dyslipidemias |
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D017311 | Amlodipine |
| D000068756 | Valsartan |
| D000069059 | Atorvastatin |
| ID | Term |
|---|---|
| D004095 | Dihydropyridines |
| D011725 | Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D013777 | Tetrazoles |
| D001393 | Azoles |
| D014633 | Valine |
| D000597 | Amino Acids, Branched-Chain |
| D000596 | Amino Acids |
| D000602 | Amino Acids, Peptides, and Proteins |
| D000601 | Amino Acids, Essential |
| D011758 | Pyrroles |
| D006538 | Heptanoic Acids |
| D005227 | Fatty Acids |
| D008055 | Lipids |
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