Cell-free Fetal DNA Concentration in Cases of Abnormal Placental Invasion .

Predictive Value of Cell-free Fetal DNA Concentration in the Maternal Plasma for Abnormal Placental Invasion in Cases of Placenta Previa.

Cell free fetal DNA might predict abnormal placental invasion

This study aims to evaluate whether measurement of cell-free fetal DNA in the maternal plasma can be predictive of abnormal invasion in cases of placenta previa.

Inclusion criteria:

1. Maternal age range from 20-40 years old.
2. Parity: para 1- para 5.
3. Body mass index range from 18-25 kg/m2.
4. Singleton pregnancy carrying male fetuses.
5. Gestational age range from 28-34 weeks.

Exclusion criteria:

1. Multifetal pregnancy.

2. Hypertension, preterm labor and intrauterine growth restriction.

3. Patients taking a tocolytic agent or those with uterine bleeding at or after blood sampling.

   • Since these complications may increase the level of cell-free fetal DNA.

4. Accidental hemorrhage.