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To evaluate the efficacy and safety of Anti-VEGF instead of intraoperative fan-shaped photocoagulation in BRVO combined with vitreous hemorrhage.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| anti-VEGF | Experimental | vitreoretinal surgery combined with intraoperative anti-VEGF |
|
| fan-shaped photocoagulation | Active Comparator | vitreoretinal surgery combined with fan-shaped photocoagulation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| anti-VEGF | Procedure | vitreoretinal surgery combined with intraoperative anti-VEGF |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Mean change from baseline in best-corrected visual acuity (BCVA) | Assessed using the ETDRS protocol | 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Mean change from baseline in visual field | Assessed on Humphery(30-2 and 60-4) | 3 years |
| chang from baseline in structure of retina | Assessed on Optical Coherence Tomography(OCT) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yong Wei, M.D | Contact | +86 15057551266 | weiyongdoctor@163.com | |
| Wei Lin, M.D | Contact | +86 13587560390 | linweiysg@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Yong Wei, M.D | The Eye Hospital of Wenzhou Medical University | Principal Investigator |
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| ID | Term |
|---|---|
| D012170 | Retinal Vein Occlusion |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
| D020246 | Venous Thrombosis |
| D013927 | Thrombosis |
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| fan-shaped photocoagulation |
| Procedure |
vitreoretinal surgery combined with intraoperative fan-shaped photocoagulation |
|
| 3 years |
| chang from baseline in retinal neovascularization | Assessed on Fundus Fluorescein Angiography(FFA) | 3 years |
| D016769 |
| Embolism and Thrombosis |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |