Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Postoperative delirium (POD) and postoperative cognitive decline (POCD) are common after surgeries in the elderly, especially after cardiothoracic surgery. These conditions are associated with adverse short- and long-term outcomes.
Multiple conditions in the perioperative period have been proposed as risk factors of POD and POCD.
Incidences vary across institutions due to differences in screening and diagnostic tools.
This is a prospective observational study to identify the incidences and risk factors of postoperative delirium and postoperative cognitive decline after elderly patients undergoing cardiac surgical procedures which require cardiopulmonary bypass and postoperative intensive care unit (ICU) admission.
Patients will be screen for POD and POCD with various psychological tests in the postoperative period and after hospital discharge.
Perioperative data and outcomes will be used to identify risk factors of both conditions.
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative delirium | A result consistent with postoperative delirium by using Confusion Assessment Method-ICU (CAM-ICU) in the postoperative period | Postoperative day 1-5 (5 consecutive days) |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative cognitive dysfunction - postoperative | A result consistent with postoperative cognitive dysfunction by using Montreal Cognitive Assessment (MOCA) | Postoperative day 5-9 (5 consecutive days) |
| Postoperative cognitive dysfunction - 3 month |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Elderly patients (age 65 and older) undergoing cardiopulmonary bypass- assisted surgery with anticipated postoperative intensive care unit admission
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Siriraj Hospital | Bangkok | 10700 | Thailand |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D000071257 | Emergence Delirium |
| D000079690 | Postoperative Cognitive Complications |
| ID | Term |
|---|---|
| D003693 | Delirium |
| D003221 | Confusion |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
Not provided
Not provided
Not provided
Not provided
Not provided
A result consistent with postoperative cognitive dysfunction by using Montreal Cognitive Assessment (MOCA)
| At 3rd month after hospital discharge |
| Postoperative cognitive dysfunction - 1 year | A result consistent with postoperative cognitive dysfunction by using Montreal Cognitive Assessment (MOCA) | At 12th month after hospital discharge |
| D009422 |
| Nervous System Diseases |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D060825 | Cognitive Dysfunction |
| D003072 | Cognition Disorders |