Thiamin Against Robust IBD Fatigue

Thiamin Against Robust IBD Fatigue

Patients with Inflammatory Bowel Disease (IBD), disease in remission and chronic fatigue will receive oral Thiamine treatment for 4 weeks in a RCT, cross-over study.

Patients with Inflammatory Bowel Disease (IBD), disease in remission and chronic fatigue will receive high dose oral Thiamine treatment for 4 weeks in a RCT, cross-over study.

After the high dose treatment period, participants will be randomized to 3 months treatment with Thiamine 300mg/day or placebo.

Inclusion Criteria:

• Inflammatory Bowel Disease
• Disease in remission
• Chronic fatigue

Exclusion Criteria:

• Co-morbidity that can explain fatigue
• Pregnancy
• Non-compliance to the study procedures
• Possible surgery in the study period