Acute pulmonary embolism is a potentially life-threatening disease with short-term mortality ranges from less than 1% to more than 30% during the hospital stay. Recent guidelines recommend to tailor diagnosis hospitalization and acute treatment based on the estimated risk for short-term Death.

The assessment of the contemporary clinical management of patients with acute pulmonary embolism across different specialties would be of crucial value.

This is a prospective, non-interventional, multicenter study in patients with acute pulmonary embolism admitted to Cardiology, Emergency and Internal Medicine Departments in Italy.

The aim of the study is to assess contemporary management strategies in patients with acute pulmonary embolism in terms of diagnosis, risk stratification, hospitalization and treatment in Italy and assess

1. their association with in-hospital and 30-day mortality and
2. their adherence to current guidelines of the European Society of Cardiology (ESC).

Inclusion Criteria:

• Patients with acute, symptomatic acute pulmonary embolism
• Age ≥ 18 years
• Informed consent

Exclusion Criteria:

• refusal of informed consent
• participation in controlled trials on the management of patients with acute pulmonary embolism

Acute symptomatic objectively diagnosed pulmonary embolism (first or recurrent).