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The purpose of the study is to determinate the antinflammatory effects of the Proxelan on a cohort of patients affected by prostatitis'like symptoms and clinical evidence of abacterical prostatistis, trough a significative improvements of pain symptoms according to the NIH-CPSI questionnaire items, spermatozoa motility/concentration variations and the semen cytokines level decrease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with prostatitis-like symptoms | Experimental | Cohort of patients with CP/CPPS (abacterial prostatitis) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Proxelan | Drug | Administration of one suppository of proxelan once a day for 30 days |
|
| Measure | Description | Time Frame |
|---|---|---|
| National Institutes of Health - Chronic Prostatitis Symptom (NIH-CPS) questionnaires score | Evaluation of pain symptoms trough NIH-CPS questionnaires' pain items (0-6). Values from 0 to 3 normal/slight symptoms; Values from 3 to 6 moderate symptoms; Values over 6 severe symptoms. | 30 days |
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Inclusion Criteria:
- prostatitis like symptoms for at least three months
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| AOUP Ospedale cisanello | Recruiting | Pisa | Tuscany | 56124 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22617307 | Background | Galeone G, Spadavecchia R, Balducci MT, Pagliarulo V. [The role of Proxelan in the treatment of chronic prostatitis. Results of a randomized trial]. Minerva Urol Nefrol. 2012 Jun;64(2):135-41. Italian. |
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| ID | Term |
|---|---|
| D011472 | Prostatitis |
| D061686 | Premature Ejaculation |
| ID | Term |
|---|---|
| D011469 | Prostatic Diseases |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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| ID | Term |
|---|---|
| C574044 | Proxelan |
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| D052801 |
| Male Urogenital Diseases |
| D000097910 | Ejaculatory Dysfunction |
| D012735 | Sexual Dysfunction, Physiological |
| D020018 | Sexual Dysfunctions, Psychological |
| D001523 | Mental Disorders |