Medication Adherence in Patients With Liver Cirrhosis

Medikamentenadhärenz Bei Patientinnen Und Patienten Mit Leberzirrhose

With this unfunded, investigator-initiated prospective, observational, explorative, single-arm and diagnostic single-centre study the investigators aim to evaluate medication adherence in patients with advanced liver cirrhosis

The main objective of the study is to investigate drug adherence in cirrhotic patients and to gain a better understanding of the causes of deficient adherence including evaluation for medication beliefs, satisfaction, depression, anxiety and health-related quality of life. A number of long-term medications have been approved for this group of patients in various indications and / or recommended by guidelines. However, adherence has not been adequately investigated yet. The investigators aim to focus on the following groups of ingredients / classes:

• Primary and secondary antibiotic prophylaxis (e.g. Norfloxacin)
• Non-selective beta-blockers (e.g. Carvedilol and Propranolol)
• diuretics (Spirolactones [e.g. Spironolacton], loop diuretics) Methodically, this is will be investigated in particular by taking into account the patients history, standardized questionnaires and validated interviews.

Inclusion Criteria:

• Treatment at Dept. of Gastroenterology, Hepatology and Endocrinology at Med. School of Hannover
• Liver cirrhosis
• Written consent for the use of personal data and health data for the purpose of this study

Exclusion Criteria:

• lack of written consent
• No consent ability
• Lack of literacy
• Inadequate knowledge of German language