Measuring Erythrocyte Iron Incorporation From Different Dosing Regimens in Anemic Women

Defining Systemic Control of Iron Absorption to Optimize Oral Iron Supplementation Regiemns for Women With Iron Deficiency Anemia

Iron-deficient anaemic subjects are likely to benefit most from oral iron supplements, but supplementation schedules vary widely in clinical practice, absorption is low and compliance is poor due to mild gastrointestinal side effects. The investigators will compare iron absorption from labeled oral iron doses of 100mg and 200mg administered either on two consecutive days or on alternate days in young anemic women.

Inclusion Criteria:

• Ferritin <15 µg/L
• Hb 8-11.9 g/dl
• BMI 18.5-24.9 kg/m2
• Body weight <70 kg

Exclusion Criteria:

• Severe anemia (Hb <8 g/dl)
• Elevated CRP >5.0 mg/L
• Chronic disease
• Long-term medication, except contraception
• Consumption of Mineral and Vitamin supplements within the study period
• Therapeutic iron infusion over the past 6 months
• Pregnancy or breastfeeding
• Smoking