The Effect of Colistin Inhalation on Ventilator Associated Pneumonia

The Effect of Colistin Inhalation on the Clinical Outcome of Patients With Ventilator Associated Pneumonia

The study has been conducted to measure the clinical outcome of early intervention with colistin inhalation in patients with ventilator associated pneumonia suspected to have multidrug resistant gram -ve bacteria

Inclusion Criteria:

• Age 18 years

Patients presenting with signs of infection 48 hours of intubation

Exclusion Criteria:

• Patients with documented bronchiectasis

Cystic fibrosis Known allergy to polymyxin. Patients presenting with chest infection or signs of infection before intubation.

Patients with creatinine clearance less than 30ml/min.