Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study is a clinical trial that will determine if sauna bathing improves blood vessel health in adults aged 50-70 years with heart disease.
Mounting evidence suggests that heat therapy may improve cardiovascular health. Recent analyses of a large cohort of middle-aged to older Finnish men have established that frequent sauna bathing is associated with a reduced risk of cardiovascular mortality, of developing dementia and Alzheimer's disease, and of developing hypertension. Given the observational nature of these relationships, it remains unknown if the beneficial effects of sauna bathing can be directly attributed to heat exposure.
The objective of this study is to test the primary hypothesis that 8 weeks of sauna bathing improves flow-mediated dilation, a measure of blood vessel health, in middle-aged to older adults (50-70 yrs) with stable coronary artery disease.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | No Intervention | Participants randomized to the control condition will be asked to maintain their normal daily habits. | |
| Sauna | Experimental | The sauna intervention will consist of 20 to 30 minute sauna bathing sessions within a dry Finnish sauna, performed 4 times per week. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lifestyle intervention | Other | Sauna bathing |
|
| Measure | Description | Time Frame |
|---|---|---|
| Flow-mediated dilation | Brachial artery flow-mediated dilation in response to 5 minutes of forearm occlusion | Change from baseline after 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Post-occlusion reactive hyperaemia (AUC) | Vascular conductance area-under-the-curve during reactive hyperaemia induced by 5 minutes of forearm occlusion | Change from baseline after 8 weeks |
| Post-occlusion reactive hyperaemia (Peak) |
| Measure | Description | Time Frame |
|---|---|---|
| Blood pressure | Systolic blood pressure at rest | Change from baseline after 8 weeks |
| Central arterial stiffness | Carotid-femoral pulse wave velocity |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cardiovascular Prevention and Rehabilitation Centre of the Montreal Heart Institute | Montreal | Quebec | H1T1N6 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37650138 | Result | Debray A, Gravel H, Garceau L, Bartlett AA, Chaseling GK, Barry H, Behzadi P, Ravanelli N, Iglesies-Grau J, Nigam A, Juneau M, Gagnon D. Finnish sauna bathing and vascular health of adults with coronary artery disease: a randomized controlled trial. J Appl Physiol (1985). 2023 Oct 1;135(4):795-804. doi: 10.1152/japplphysiol.00322.2023. Epub 2023 Aug 31. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Peak vascular conductance during reactive hyperaemia induced by 5 minutes of forearm occlusion
| Change from baseline after 8 weeks |
| Local skin heating-induced vasodilation | Plateau of the cutaneous vascular conductance response during local heating of the skin to 39°C | Change from baseline after 8 weeks |
| Change from baseline after 8 weeks |
| Heart rate variability | Resting levels of heart rate variability | Change from baseline after 8 weeks |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |