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Intravitreal injections are an efficient method for delivering intraocular therapeutic agents in numerous ophthalmologic diseases. However, side effects, such as pain and subconjunctival hemorrhage remain a major concern.
Prevention or alleviation of those side effects might shorten the healing duration and improve patients' quality of life.
cooling the eye using ice patched prior to Intravitreal injections may ameliorated pain and subconjunctival hemorrhage incidences.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ice | Active Comparator | Patients were randomly assigned to receive an ice 5 minutes prior the IViT |
|
| placebo | Placebo Comparator | Patients were randomly assigned to a room temperature patch (placebo) 5 minutes prior the IViT |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ice pack | Other | ice pack was placed on eyelid 5 minutes prior to IVIT |
| |
| Measure | Description | Time Frame |
|---|---|---|
| pain | Visual Analogue Scale (VAS) is a Likert-type scale (1-10). The VAS is a reliable tool in evaluating and quantifying ocular discomfort | change between VAS pain score at baseline and 10 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| size of subconjunctival hemorrhage | subconjunctival hemorrhage in mm | change between subconjunctival hemorrhage at baseline and 10 minutes |
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Inclusion Criteria:
patients receiving intravitreal injection
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The E.Wolfson Medical Center | Holon | 58100 | Israel |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| room temperature pack |
| Other |
room temperature pack was placed on eyelid 5 minutes prior to IVIT |
|