Enrolling by invitationInterventionalPhase 2Updated Jun 12, 2026
Neuroimaging Study
Neuroimaging Study
ClinicalTrials.gov ID
NCT03618186
Lead Sponsor
Mayo ClinicOTHER
Overall Status
Enrolling by invitation
Study Type
Interventional
Phase
Phase 2
Enrollment
240Estimated
Last Update Posted
Jun 12, 2026Actual
Start Date
Nov 26, 2018Actual
Primary Completion Date
May 2030Estimated
Completion Date
May 2030Estimated
Official Title
Neuroimaging Study
Brief Summary
The researchers are trying to gather information and learn more about imaging tests in racially different people who are cognitively normal or have dementia.
Cognitive Impairment
Tau PET scan
Ages Eligible for Study
Adult (18-64)Older Adult (65+)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
Yes
Eligibility Criteria
Inclusion Criteria:
Male or female African Americans 30 years of age or older
Subjects who have completed or are scheduled to undergo the neurological evaluation procedures described below.
Exclusion Criteria:
Subjects unable to lie down without moving for 20 minutes.
Women who are pregnant or cannot stop breast feeding for 24 hours.
Claustrophobic patients unable to tolerate the scans.
Subjects with a prolonged QT interval (as demonstrated by ECG test) cannot participate in the Tau-PET scans.
Standard safety exclusionary criteria for MRI such as metallic foreign bodies, pacemaker, etc, since the quantitative PET data analysis is based on anatomic criteria that are established uniquely for each subject by registration to his/her MRI.