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Empirically, mosturizer is used to prevent and treat many occupational dermatoses that has skin barrier impairment. Evidence based medicine about the effectivity of mosturizer in occupational dermatoses is limited. Coconut oil is one of traditional substance that is used as a skin care. There is study shows that coconut oil is effective for atopic dermatitis treatment in children. Other studies are needed to assess the effectivity coconut oil mosturizer cream to overcome occupational hand dermatitis.
The aim of this study is to measure the effectivenes of coconut oil cream for batik workers who suffer from occupational hand dermatitis. The gloves that used as a protective equipment are made from rubber which have its own limitations. Therefore other interventions are needed to improve barrier skin.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Coconut Oil Cream | Active Comparator | This group consist of batik traditional workers who use coconut oil cream for 2 weeks. |
|
| Placebo Cream | Placebo Comparator | This group consist of batik traditional workers who use placebo cream which contained the vehiculum of the cream; using for 2 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cocos Nucifera Whole | Drug | Applying the Cocos Nucifera Whole cream for 2 weeks, on both of arms. We evaluated the score of hand dermatitis using Hand Eczema Score Index ( HECSI), transepidermal water loss (TEWL), and Skin capacitance |
| Measure | Description | Time Frame |
|---|---|---|
| clinical improvement of hand dermatitis measured by Hand Eczema Severity Index (HECSI) after using coconut oil | Batik workers who had hand dermatitis was measured using HECSI score before and after intervention with coconut oil cream. They used the cream twice daily for 14 days | 14 days |
| Measure | Description | Time Frame |
|---|---|---|
| Transepidermal water loss (TEWL) | TEWL is the amount of water that passively evaporates through skin to the external environment | 14 days |
| Skin capacitance | Skin capacitance depends on the water content of the stratum corneum |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Retno W Soebaryo, Prof | Fakultas Kedokteran Universitas Indonesia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine Universitas Indonesia | Jakarta Pusat | Jakarta Special Capital Region | 10430 | Indonesia |
There is no plan to make individual participant data
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| ID | Term |
|---|---|
| D006229 | Hand Dermatoses |
| ID | Term |
|---|---|
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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Batik traditional workers with occupational hand dermatitis using emolient for prevention
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blinding had to be done by Clinical Research Supporting Unit Faculty of Medicine, Universitas Indonesia
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| Cocos Nucifera Whole | Drug | For dermatopharmacokinetic evaluation using tape/ skin stripping |
|
|
| 14 days |