The Mechanism and Prognosis of Pulmonary Circulation Dysfunction

The Mechanism and Prognosis of Pulmonary Circulation Dysfunction in Pulmonary Injury and Recovery

Venous thromboembolism (VTE) is a condition which influenced by both environmental and genetic factors. This study is going to explore new significant Single nucleotide polymorphisms (SNPs) associated with VTE by Genome-Wide Association Studies (GWAS) and bioinformatics analysis. Transcriptomics and cytokine antibody array are also used to find new biomarkers of VTE's early diagnosis, severity and prognosis.

Inclusion Criteria:

• Chinese Han population older than 14 years old
• Acute VTE patients diagnosed in 1 month
• With informed consent

Exclusion Criteria:

• Patients with psychosis
• Patients with contraindications for computed tomographic pulmonary angiography (CTPA)
• Chronic VTE
• Recurrence of chronic VTE