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The biological diagnosis of the primary hyperparathyroidism is now facilitated by the reliability of the balance of phosphate and calcium and the dosage of parathyroid hormone (PTH).
This diagnosis of preoperative localization is important as surgery are now targeted to the responsible lesion.
The "gold standard" for this localization is the cervical ultrasound exploring the usual sites of adenomas and a MIBI scintigraphy (the parathyroid adenoma significantly concentrating this cell marker).
However, the diagnosis of preoperative localization remains a subject of discussion as to the most appropriate tests. Indeed, the morphological diagnosis is performed at the ultrasound stage in more than half the cases. It is the new performance of this morphological examination that makes it possible to obtain these results.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cervical ultrasound | Other | cervical ultrasound will be realized by a endocinologist trained in the cervical ultrasound |
|
| Measure | Description | Time Frame |
|---|---|---|
| Adenoma parathyroid diagnosed using cervical ultrasound | Adenoma parathyroid diagnosed using cervical ultrasound. Cervical ultrasound will be realized by a endocrinologist trained in the cervical ultrasound and not informed of the results of the echoscintigraphy | Day 0 |
| Adenoma parathyroid diagnosed using echoscintigraphy | Adenoma parathyroid diagnosed using echoscintigraphy. Echoscintigraphy will be realized by a nuclear physician not informed of the results of the cervical ultrasound | Day 0 |
| Adenoma parathyroid diagnosed using anatomopathology | Adenoma parathyroid diagnosed by anatomopathologist, after surgery. | Day 0 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Brigitte DELEMER | Contact | 0326788101 | bdelemer@chu-reims.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Damien JOLLY | Recruiting | Reims | France |
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| ID | Term |
|---|---|
| D049950 | Hyperparathyroidism, Primary |
| ID | Term |
|---|---|
| D006961 | Hyperparathyroidism |
| D010279 | Parathyroid Diseases |
| D004700 | Endocrine System Diseases |
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