Low Molecular Weight Heparin in Pregnancies With Unexplained Stillbirths

Second Generation Low Molecular Weight Heparin (Bemiparin) as a Prophylactic for Management of Subsequent Pregnancy After an Unexplained Stillbirth: A Clinical Comparative Study

Bemiparin for pregnant women with abnormal umbilical artery Doppler ultrasound

152 women with history of unexplained stillbirths were identified , umbilical arty Doppler ultrasound was conducted for them at 20-22 weeks gestation . they were divided into two group , group one are those with abnormal resistant index (= or more than 0.6) thy received Bemiparin 2500 IU subcutaneously daily up to 24 hours before delivery .

Group 2 with normal umbilical artery resistant index received no any interventions just routine antenatal follow up .

Inclusion Criteria:

• Second pregnancy after previous unexplained fetal death
• Singleton pregnancy
• No any medical disorders during pregnancy like diabetes or Systemic Lupus Erythematosus
• Normally located placenta
• No congenital fetal anomalies
• Patient accept to participate

Exclusion Criteria:

• Confirmed thrombophilia
• Twin pregnancies
• Refused to participate