Laparoscopic prostatectomy (LP) is characterized by substantial tissue trauma, despite its minimally -invasive approach. Although postoperative pain intensity is lower when compared to open procedures, the use of opioids is common. Retrospective review of available LP cases revealed that although analgesic demand varied, nearly all of our LP patients required opioids postoperatively. Bilateral Quadratus Lumborum Block (QLB), being one of relatively new features of regional anesthesia, offers good analgesia of abdominal wall, with the potential for control of visceral pain. This study was established to evaluate its effectiveness in alleviating pain after radical prostatectomy in a double - blind, placebo - controlled manner.

Inclusion Criteria:

• ASA status less or equal 3
• Scheduled for transperitoneal or extraperitoneal endoscopic prostatectomy
• Able to understand information provided and to sign the informed consent for participation in the study

Exclusion Criteria:

• known allergy to local anesthetics and opioids
• infection in the area of block placement
• known chronic use of opioids, gabapentinoids and tricyclic antidepressants
• mental inability to understand the principles and rules of patient-controlled analgesia pump

Solution used for block (local anesthetic or placebo) is known to anesthetist not involved in patient's care.