Regional vs General Anesthesia in Patients With Hip Fracture Under Treatment With Clopidogrel

Regional vs General Anesthesia in Patients With Hip Fracture Under Treatment With Clopidogrel

This study compares general to regional anesthesia concerning morbidity and mortality in patients older than or equal to 65 years old who receive clopidogrel and are to be submitted in hip fracture surgery. Half of participants will receive general anesthesia the first 48 hours and the other half will receive regional anesthesia after 5 days of the discontinuation of clopidogrel.

Inclusion Criteria:

• Patients older than or equal to 65 years old with hip fracture
• Native language greek and capable of speaking and writing
• Primary school graduated
• Is about to undergo in orthopedic surgery
• Participants should be available until the end of the prefixed end date of the research

Exclusion Criteria:

• Severe hearing impairment and visual acuity
• Major cognitive impairment (Mini Mental State Examination <24)
• Medical history of central nervous system disease including stroke with neurological deficit
• Medical history of alcohol or drug abuse
• Dementia, Parkinson disease, Alzheimer disease
• Contraindication for general or regional anesthesia
• Severe contraindication for antiplatelet agent discontinuation
• Multiple failures
• Receiving other coagulants
• No written consent