Neurodynamic Interventions for Multiple Sclerosis

Effects of Neurodynamic Interventions to Multimodal Physical Therapy in Patients With Multiple Sclerosis

A randomized, parallel-group, clinical trial will be conducted to compare the immediate effects of the inclusion of a neurodynamic intervention into a multimodal physiotherapy program on pressure pain sensitivity, pain and manual dexterity in patients with multiple sclerosis

Inclusion Criteria:

• a diagnosis of multiple sclerosis according to the modified McDonald criteria;
• symptoms of paresthesia and lack of sensitivity in the upper extremity;
• Expanded Disability Status Scale (EDSS) between 0 and 6.5 points;
• absence of cognitive deficit.

Exclusion Criteria:

• any exacerbation of multiple sclerosis during the previous 3 months;
• previous hand surgery or steroid injections treatment in the upper extremity;
• multiple diagnoses on the upper extremity (e.g., cervical radiculopathy);
• cervical, shoulder, or upper extremity trauma;
• other comorbid musculoskeletal medical conditions;
• mini-mental state examination <25