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Due to the study sponsor's request to prematurely terminate this study, the numbers of participants enrolled in the study discontinued or some discontinued earlier due to a screening failure.
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| Name | Class |
|---|---|
| University of Southern Queensland | OTHER |
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The purpose of this study is to identify whether the combination of coconut Nourish and Queen Garnet plum are able to attenuate ageing-related complications, including muscle mass loss and inflammation. The study endpoints will measure muscle mass as the primary endpoint with blood lipids, glucose, blood pressure, and inflammatory markers serving as some of the secondary endpoints. As the two products are rich in dietary fibre and anthocyanins, respectively, the study outcome will help to understand role of these dietary components in improving complications that are seen quite frequently in elderly population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treatment cookies | Experimental |
| |
| Control cookies | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Treatment cookies | Other | Plain flour, Coconut Nourish, Queen Garnet Plum, Unsalted Butter, Artificial Sweetener |
|
| Measure | Description | Time Frame |
|---|---|---|
| Lean mass | Measured using dual-energy x-ray absorptiometry (DXA) | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Body weight | 8 weeks | |
| Body mass index | Weight and height will be combined to report BMI in kg/m^2 | 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Peter Jones, PhD | University of Manitoba | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Southern Queensland | Toowoomba | Queensland | 4350 | Australia | ||
| Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba |
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| Control cookies | Other | Plain flour, Coconut Powder, Unsalted Butter, Artificial Sweetener, Food Colour |
|
| Waist circumference |
| 8 weeks |
| Arm circumference | 8 weeks |
| Wrist circumference | 8 weeks |
| Calf circumference | 8 weeks |
| Triceps skinfold | 8 weeks |
| Five times chair standing test | 8 weeks |
| Handgrip dynamometer | 8 weeks |
| Blood pressure | Systolic and diastolic pressure will be assessed | 8 weeks |
| Heart rate | 8 weeks |
| Bone mineral density | Measured using DXA | 8 weeks |
| Bone mineral content | Measured using DXA | 8 weeks |
| Fat mass | Measured using DXA | 8 weeks |
| Blood total cholesterol | 8 weeks |
| Blood low-density lipoprotein cholesterol | 8 weeks |
| Blood high-density lipoprotein cholesterol | 8 weeks |
| Blood triglycerides | 8 weeks |
| Blood glucose | 8 weeks |
| Blood C-reactive protein | 8 weeks |
| Blood interleukin 1 beta | 8 weeks |
| Blood tumor necrosis factor alpha | 8 weeks |
| Winnipeg |
| Manitoba |
| R3T 6C5 |
| Canada |