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During the last decades, assisted reproductive technique has been transformed from a miracle to real and has become widely used for treatment human infertility.
this was associated with increased the rate of twin pregnancies
Twin pregnancies are associated with an increased risk of maternal mortality & morbidity and an increase in the incidence of neonatal morbidity and mortality compared to singleton pregnancy.
The heterogeneous results reported so far can also depend on differences in the studied populations and/or in the management approach to twin pregnancy, variability in data regarding neonatal and maternal outcomes.
Evidence on pregnancy outcomes of twins conceived by artificial reproductive technology (ART) compared with those naturally conceived (NC) is conflicting, A 2004 systematic review and a large 2008 study both were praised that in cases of twin pregnancy after assisted conception the perinatal mortality is significantly lower, when compared with those spontaneously conceived .
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| Measure | Description | Time Frame |
|---|---|---|
| Maternal diabetes using glucose tolerance test | The diagnosis of GDM was based a fasting plasma glucose level of ≥5.6 mmol/L with 2 h plasma glucose level of ≥7.8 mmol/L | up to 7 days postpartum |
| Hypertension during pregnancy and preeclampsia diagnosed using ACOG guideline a) weight in kilogram b) Apgar score in first and 10th minutes c)Admission to neonatal intensive acre unit measured in days | Systolic and diastolic blood pressure equal or more than140/90 mm Hg measured on two or more occasions after 20 weeks of gestation in previously normotensive women, with or without proteinuria (proteinuria of >100 mg/dL by urine analysis, or >300 mg/24 h) | up to 1 week postpartum |
| Maternal anemia using WHO criteria | Hemoglobin level less than 11gm/dl | up to 1 week |
| Postpartum hemorrhage | Bleeding from genital tract of 500 mL or more vaginally | up to 1 week |
| Neonatal weight in kilogram | categorized as extreme low birth weight (LBW) for <1000 g, very LBW for 1000-1500 g, LBW for 1500-2500 g, and normal birth weight for >2500 g | up to 7 days |
| Neonatal Apgar(Appearance, Pulse, Grimace, Activity, and Respiration) score | Apgar scores includes 10 sores , 2 for each . The Apgar score was classified as severely depressed <0-3>, moderately depressed<4-6> and excellent condition<7-10> | first and fifth minute of life |
| Measure | Description | Time Frame |
|---|---|---|
| Maternal mode of delivery | Cesarean section or vaginal delivery | during labor |
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Inclusion Criteria:
Exclusion Criteria:
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Twin delivery was identified when coming to outpatient clinic & labour ward into two groups, first group iatrogenic conceived twins (either ART, or medical ovulation induction mainly clomiphene citrate and gonadotrophins).The second group is a twin pregnancy who conceived naturally .
Demographic characters, maternal and neonatal outcomes were compared in both groups
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| Name | Affiliation | Role |
|---|---|---|
| Diana Y. Rashid | Maternity Teaching Hospital | Principal Investigator |
| Shahla K. Alalaf | Hawler Medical University, College of Medicine | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kurdistan Board for Medical speciality | Erbil | Kurdistan Region | 44001 | Iraq |
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| ID | Term |
|---|---|
| D000071074 | Neonatal Sepsis |
| D066087 | Perinatal Death |
| ID | Term |
|---|---|
| D018805 | Sepsis |
| D007239 | Infections |
| D007232 | Infant, Newborn, Diseases |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
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| Admission to neonatal care unit in days |
Fetal care unit |
| up to 7 days |
| D018746 | Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D003643 | Death |