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Preptin and amylin are pancreatic hormones which participate in glucose homeostasis. This study aims to evaluate how serum preptin and amylin levels are altered in polycystic ovary syndrome (PCOS) patients and healthy women based on BMI groups .
Materials and Methods: This is a cross-sectional review of 40 PCOS patients and 40 healthy women who were matched with respect to BMI (<25 kg/m2 and ≥25 kg/m2).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Polycyctic ovary sendrome (PCOS) | these women who have PCOS, we will use their blood samples |
| |
| Healty groups | These women who have reguler menstrual cycle, no akne or hirsutism, we will use their boold samples |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| preptin and amylin level | Diagnostic Test | we will take both of group blood samples to compare them serum preptin and amylin |
|
| Measure | Description | Time Frame |
|---|---|---|
| Serum Preptin and Amylin Levels with Respect to Body Mass Index in Polycystic Ovary Syndrome Patients | Serum Preptin and Amylin Levels will compare between groups | six months |
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Inclusion Criteria:
the patients with PCOS
Exclusion Criteria:
Cushing's syndrome 21-hydroxylase deficiency Congenital adrenal hyperplasia Thyroid dysfunction Hyperprolactinemia Diabetes Chronic cardiovascular Hepatic, renal, and hematologic diseases Malignancies Using oral contraceptives, anti-androgens, glucocorticoids, anti-hypertensives, anti-diabetics, calcium supplements and anti-obesity drugs and those who smoke or consume alcohol
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Polycystic ovary syndrome
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| Name | Affiliation | Role |
|---|---|---|
| Senol sentürk, PhD | Recep Tayyip Erdogan University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Recep Tayyip Erdogan University | Rize | 53000 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D011085 | Polycystic Ovary Syndrome |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D010048 | Ovarian Cysts |
| D003560 | Cysts |
| D009369 | Neoplasms |
| D010049 | Ovarian Diseases |
| D000291 |
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| Adnexal Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
| D006058 | Gonadal Disorders |
| D004700 | Endocrine System Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |