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| ID | Type | Description | Link |
|---|---|---|---|
| 2017-A03451-52 | Other Identifier | ANSM |
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| Name | Class |
|---|---|
| University of Saint-Etienne | UNKNOWN |
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In order to develop an innovative device to study infectious keratitis, we need to illuminate the cornea of patients suffering from an infectious keratitis with red or near-infrared light. Because of technical reasons the shortest possible wavelength (red) presents advantages.
The aim of this preliminary study is to measure the maximal intensity tolerated during illumination with 6 wavelength corresponding : 2 red, 2 far red and 1 near infrared lights in order to determine the shortest wavelength well tolerated by patients, in comparison with the standard blue light illumination.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Light exposure | Experimental | The keratitis eye of the patient is exposed to 6 lights with increasing intensity according to a constant speed. The patients switch off the light when the discomfort is too elevated |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Light exposure | Device | The 6 lights used randomly are :
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| Measure | Description | Time Frame |
|---|---|---|
| Light intensity | For each wavelength, the highest light intensity tolerated by the patient is measured (mWatts/cm² ) | At the inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| Severity of the keratitis | It is determined by slit lamp. The result is "severe" or "not severe" | At the inclusion |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Gilles THURET, MD PhD | CHU de Saint-Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Saint-Etienne | Saint-Etienne | 42000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33038155 | Derived | Courrier E, Lambert V, Renault D, Garcin T, Moine B, Herbepin P, Thuret G, Gain P. Tolerance to Light of Patients Suffering From Infectious Keratitis. Cornea. 2021 Jan;40(1):5-11. doi: 10.1097/ICO.0000000000002516. |
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| ID | Term |
|---|---|
| D007634 | Keratitis |
| D015817 | Eye Infections |
| D020795 | Photophobia |
| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| D005128 | Eye Diseases |
| D007239 | Infections |
| D014786 | Vision Disorders |
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Each patient is its own control
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| D012678 |
| Sensation Disorders |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |