Clinical trial to determine the effect of adding a diet with low glycemic index and load to adults for the treatment of moderate acne. Adult patients with acne where recruited in two groups, A and B. Group A received a normal diet according to their metabolic status and group B received a diet with low glycemic index and load. Outcomes were measured at week 12.

Clinical trial to determine the effect of adding a diet with low glycemic index and load to adults for the treatment of moderate acne. Adult patients with acne where recruited in two groups, A and B. Both groups of treatment were treated with doxycycline 100 mg per day plus adapalene 0.1% gel daily for 12 weeks. During pharmacologic treatment, all patients had nutrition counseling monthly. Group A received a normal diet according to their metabolic status and group B received a diet with low glycemic index and load. At the end of the trial, the change in acne lesions count was analyzed and also their metabolic status. Quality of life was also measured.

Inclusion Criteria:

• Having moderate inflammatory acne
• 18 to 25 years old
• Male
• Stable weight during the last 3 months

Exclusion Criteria:

• Previous or actual isotretinoin therapy
• Antibiotic therapy or during the last 3 months
• Therapy based on peelings, dermabrasion, laser or intense pulsed light during the last 6 months
• Endocrine disorders
• Drug and alcohol consumption during the last 6 months
• Tabacco use during the last 6 months
• Lactose intolerance
• Have eating disorders or gastrointestinal disorders
• Actual nutrition therapy
• Have chronic diseases that requires pharmacologic therapy
• Severe acne that requires isotretinoin therapy

Diet intervention was made by the nutrition specialist. Neither the principal investigator nor the outcome assessor were aware about the group of diet intervention.