Oral infections can trigger the production of pro-inflammatory mediators that may be risk factors for miscarriage. The investigators investigated whether oral health care patterns that may promote or alleviate oral inflammation were associated with the history of miscarriage in Turkish women.

Power analysis was performed with the G-Power software package to determine sample size.

To cover possible data loss, 10% of a group were added to each group. Medical and dental examination will be performed both of control and experimental groups. In dental examination decayed, missing, or filled teeth (DMFT) index will be used according to World Health Organization (WHO 1997) criteria. All teeth were visually using the International Caries Detection and Assessment System (ICDAS-II).

To analyze the correlation between oral health status and miscarriage linear regression test and for comparison of both the groups (case and control), two sample t test and chi square test were used.

Inclusion Criteria:

• history of at least two unexplained recurrent miscarriage below 20th week of pregnancy
• systemically healthy females with at least two normal births
• no poor obstetric history such as preeclampsia and premature birth

Exclusion Criteria:

• history of thyroid disease, hyperprolactinemia, antiphospholipid syndrome, systemic lupus erythematosus, autoimmune diseases, thrombophilia, diabetes mellitus, uterine/cervical abnormalities, polycystic ovary syndrome, active liver disease, cardiovascular disease, premature ovarian failure, acute or chronic upper respiratory tract diseases, IVF pregnancy, multiple pregnancy, preeclampsia, arterial or venous embolism, infection,
• habit of smoking, alcohol, drug or caffeine,
• abnormal embryo karyotype,
• infection with hepatitis B or C, and HIV,
• chromosomal abnormalities,
• dental fluorosis,
• fluoride supplements,
• orthodontic appliances,
• body mass index ≥ 30 kg / m2
• age of the partner is found to be over 40

Patients were aged from 18 to 35 years, 100 females

Data will be available within 6 months of study finishing