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Uterine rupture represents an uncommon event: it is is a life-threatening obstetric complication with high maternal and perinatal morbidity and mortality. Indeed, uterine rupture may cause catastrophic maternal and fetal complications (uterine hemorrhage, hysterectomy with consequent fertility loss, maternal and fetal death or cerebral palsy) which are hardly acceptable within the context of a natural event such as birth.
Uterine rupture can occur during pregnancy, early in labor or following a prolonged labor, most frequently near or at term and, rarely, during early to mid-pregnancy. Its prevalence ranges between 0.006% for women without previous cesarean section (CS) in the western countries, to 25% for women with obstructed labor in African countries.
Pregnancy after myomectomy or CS, vaginal delivery after cesarean sections (VBACs) and vaginal delivery after myomectomy are potentially "at risk" of uterine rupture.
Despite uterine rupture is widely considered a life-threatening condition, so far most of published data refer to case reports or very small case series. In this scenario, the "Uterine Rupture International Data Acquisition" study group would like to collect a large number of events, in order to identify the potential risk factors among different populations through a multivariate analysis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Uterine rupture | Women with uterine rupture occurred during pregnancy. |
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| Measure | Description | Time Frame |
|---|---|---|
| Uterine rupture | Women with uterine rupture occurred during pregnancy. | A retrospective analysis of 10 years. |
| Measure | Description | Time Frame |
|---|---|---|
| Gestational age at uterine rupture | Gestational age, calculated as weeks and days, in which uterine rupture occurred. | A retrospective analysis of 10 years. |
| Parity | The number of previous delivery. |
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Inclusion Criteria:
Exclusion Criteria:
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Women with uterine rupture occurred during pregnancy.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Andrea Tinelli, M.D. | Contact | +393392074078 | andreatinelli@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Andrea Tinelli, M.D. | U.O. Ginecologia e Ostetricia, Ospedale Vito Fazzi, 73100 Lecce, Italy | Study Director |
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| ID | Term |
|---|---|
| D014597 | Uterine Rupture |
| ID | Term |
|---|---|
| D014591 | Uterine Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| A retrospective analysis of 10 years. |
| Body Mass Index | The Body Mass Index of each patient in which uterine rupture occurred. | A retrospective analysis of 10 years. |
| Presence of myomas | The occurrence of myomas in each patient in which uterine rupture occurred. | A retrospective analysis of 10 years. |
| Hysterectomy | The number of cases in which it was necessary to perform hysterectomy after uterine rupture. | A retrospective analysis of 10 years. |
| Hospital stay | The hospital stay from the admission to the discharge, expressed in days. | A retrospective analysis of 10 years. |
| Neonatal complications | The occurrence of neonatal complications, included neonatal deaths. | A retrospective analysis of 10 years. |
| D000091642 | Urogenital Diseases |
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D000091662 | Genital Diseases |
| D012421 | Rupture |
| D014947 | Wounds and Injuries |