Air Tamponade and Non-supine Positioning in Macular Hole Surgery.

Air Tamponade and Non-supine Positioning in Macular Hole Surgery. A Randomized Controlled Trial.

This is a prospective, multicenter, randomized non-inferiority trial, where the macular hole closure rate with intraocular air tamponade is compared to the closure rate with gas tamponade.The patients are randomized to receive either air or gas (26% SF6) as intraocular tamponade, just prior to the intraocular flushing of the tamponade during the vitrectomy procedure. Postoperatively, the patients adhere to the nonsupine regimen for three days, and the tennis ball technique is used during sleep to enhance patients' positioning compliance.

Inclusion Criteria:

• Primary macular hole ≤ 400 μm
• Duration no more than 24 months
• Able to sign informed content
• Signed informed content

Exclusion Criteria:

• Earlier vitreoretinal surgery in present eye
• Secondary macular holes caused by other conditions than vitreomacular traction
• Myopic macular hole, i.e. excessive myopia (more than -6 dioptres)
• Posttraumatic macular hole
• Macular holes secondary to retinal detachment or other retinal diseases
• Surgery under general anesthesia
• Visual acuity below 20/40 in fellow-eye