Incidence of Trauma Induced Coagulopathy in Patients With Prehospital Administration of Fibrinogen

Incidence of Trauma Induced Coagulopathy in Patients With Prehospital Administration of Fibrinogen

The purpose of the study is to find out the incidence of trauma induced coagulopathy in patients with severe trauma who received fibrinogen prior admission to emergency department during prehospital care.

The study will commence following the Approval by The Ethics Research Committee. All patients admitted to emergency department during the study will be enrolled after fulfilling the inclusion criteria and in the absence of any exclusion criteria. Informed consent will be requested. After admission to emergency department the blood samples will be taken and blood tests and viscoelastic tests will be performed. All data and results will be entered in the study form. Statistical analysis will be performed and incidence of trauma induced coagulopathy estimated. In addition, 28-day mortality and the incidence of thromboembolic complications will be monitored.

Inclusion Criteria:

• multiple trauma, injury severity score (ISS) ≥16
• administration of fibrinogen in prehospital care
• age 18-80 years

Exclusion Criteria:

• ISS 75
• pregnancy
• therapeutic anticoagulation
• therapeutic antiaggregation