Endocuff Vision Colonoscopy vs. AmplifEYE Colonoscopy

Comparison of Endocuff Vision to Medivators AmplifEYE for Detection of Precancerous Colorectal Polyps.

The study aims to compare the results between colonoscopies with two different attachments on the distal end of the colonoscope.

This will be a prospective, randomized controlled study. Subjects referred for a screening, surveillance, or diagnostic colonoscopy will be prospectively enrolled. This study aims to compare the number of adenomas detected per colonoscopy (APC) between an Endocuff colonoscopy and an AmplifEYE colonoscopy.

It is estimated that the Endocuff Vision will result in an APC of 2.3. The investigators consider that a clinically acceptable ADR for the Medivators device would be within 20% of this value or 1.5.

Inclusion Criteria:

• 40 years of age or older
• Undergoing colonoscopy for screening, surveillance, or diagnostic purposes
• Able to provide written informed consent

Exclusion Criteria:

• Active Inflammatory Bowel Disease
• Prior resection of the colon
• Referred for resection of a polyp identified by another physician
• Referred for a previous incomplete colonoscopy