Endoscopic Resection of Non-ampullary Duodenal Adenomas: Endoscopic Mucosal Resection (EMR) vs. Endoscopic Full-thickness Resection With the 'Duodenal Full-thickness Resection Device' (dFTRD)

Endoscopic Resection of Non-ampullary Duodenal Adenomas: Endoscopic Mucosal Resection (EMR) vs. Endoscopic Full-thickness Resection With the 'Duodenal Full-thickness Resection Device' (dFTRD)

Prospective, randomized multi-center trial. Comparison of Endoscopic Mucosal Resection (EMR) versus Endoscopic Full-Thickness Resection with the duodenal Full-Thickness Resection Device (dFTRD) of non-ampullary duodenal adenomas.

Prospective, randomized multi-center trial. Comparison of Endoscopic Mucosal Resection (EMR) versus Endoscopic Full-Thickness Resection with the duodenal Full-Thickness Resection Device (dFTRD) of non-ampullary duodenal adenomas.

Inclusion Criteria:

• duodenal adenoma
• age 18 or older
• written informed consent

Exclusion Criteria:

• duodenal adenomas with a size > 25 mm
• duodenal adenomas with 20 mm or less distance to the major and/or minor duodenal papilla
• presence of two or more duodenal adenomas
• suspected or histologically confirmed malignancy
• tumor disease (exception: after successful curative treatment)
• conditions/diseases of the upper GI-tract that impair advancing of the devices into the duodenum
• moribund patient
• pregnancy and breastfeeding
• patients that cannot give informed consent (e.g. psychiatric disorders, language barrier,...)
• other contraindications for duodenal resections