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| Name | Class |
|---|---|
| University of Copenhagen | OTHER |
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This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury
This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury using two clinically developed programmes and one sham-intervention. Furthermore, the study consists of Groups that receives the computerized training both with and witouth support from a professional.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Brain+ with clinical support | Experimental | Intervention: Computer based cognitive rehabilitation. This group will train with the programme 'Brain+' and receive continuous support from a clinician during the intervention period. |
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| Cogmed with continuous support | Experimental | Intervention: computer based cognitive rehabilitation. This group will train with the programme 'Cogmed' and receive continuous support from a clinician during the intervention period. |
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| Brain+ without support | Experimental | Intervention: computer based cognitive rehabilitation. This group will train with the programme 'Brain+' but receive no support during the intervention period. |
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| Sham-training group | Sham Comparator | Intervention: Sham computerized gaming. This group will train computerized solitaire and other computerized games which are thought to be generally cognitive stimulating but with a very limit load on executive functions. This group will receive continuous support during the intervention period. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Computer based cognitive rehabilitation | Behavioral | Computer based cognitive rehabilitation is a supplementary computerized tool for cognitive rehabilitation design to train various cognitive functions. Many programmes are available. The current study investigates the effects on two such programmes on rehabilitation of executive functions in the chronic phase after acquired brain injury. |
| Measure | Description | Time Frame |
|---|---|---|
| PASAT | Paced auditory serial addition test, test of verbal working memory | 3 seconds |
| Trail making test A+B | Trail test A: Test of visual attention, trail test B: Test of visual working memory and cognitive shifts | 5 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| SDMT | Symbol digit modalities test: Test of processing speed | 90 seconds |
| Word fluency test | Test of verbal fluency | 1 min |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jesper Mogensen, Professor | University of Copenhagen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Center for Hjerneskade | Amager | København | 2300 | Denmark |
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| ID | Term |
|---|---|
| D001930 | Brain Injuries |
| D019954 | Neurobehavioral Manifestations |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D006259 | Craniocerebral Trauma |
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Patients know that one of the conditions is a control-condition not expected to have significant clinical effects (required by the danish scientific committee), but they don't know which treatment condition they are randomised to. The outcome assessor is blind to the group allocation of patients.
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| Sham computerized gaming | Other | Sham training with generally stimulating computer-games |
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| Digit span (WAIS-IV) | Test of verbal memory (forward) and working memory (backward) | 5 minutes |
| Spatial span (WMS-III) | Test of visuospatial memory (forward) and visuospatial working memory (backward) | 5 minutes |
| Stroop colour and word test | Test of inhibition | 3 minutes |
| BNI-FS | Barrow Neurological Institute Fatigue Scale: Test of fatigue after brain injury | 10 minutes |
| Quality of Life after Brain Injury (QOLIBRI) | Questionnaire about quality of life | 10 minutes |
| Wordlist, Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) | Verbal memory test | 10 minutes |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |