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| ID | Type | Description | Link |
|---|---|---|---|
| CDMRP-PR171647 | Other Grant/Funding Number | DoD |
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| Name | Class |
|---|---|
| United States Department of Defense | FED |
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The purpose of this study is to determine changes to knee joint loading, biological markers, and cartilage structure following a novel active feedback gait retraining program in anterior cruciate ligament reconstructed patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gait retraining | Experimental | Eight weeks of active-feedback gait retraining. The gait retraining device measures pressure/force under the lateral side of the foot and activates vibration if loading crosses a set threshold. The location of the vibration is customized for each subject to achieve maximal sensitivity. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Active feedback gait retraining | Device | The device measures pressure/force under the lateral side of the foot and activates vibration if loading crosses a set threshold. The location of the vibration is customized for each subject to achieve maximal sensitivity. |
| Measure | Description | Time Frame |
|---|---|---|
| Knee Adduction Moment | Knee Joint Loading (%Bw*Ht) will be assessed at baseline and immediately after gait retraining | Change from baseline to immediately after 8 weeks of retraining |
| Measure | Description | Time Frame |
|---|---|---|
| Medial knee compartment qMRI | Changes to quantitative MRI measures at 6 months after retraining will be correlated with changes to joint loading | Change from baseline to 6 months after retraining |
| Knee Adduction Moment |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jennifer Hledik, PhD | Contact | 650-493-5000 | 62388 | jerhart@stanford.edu |
| Jessica Asay, MS | Contact | asay@stanford.edu |
| Name | Affiliation | Role |
|---|---|---|
| Constance Chu, MD | VAPAHCS and Stanford University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| VA Palo Alto | Recruiting | Palo Alto | California | 94304 | United States |
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Knee Joint Loading (%Bw*Ht)
| Change from baseline to 3 months after retraining |
| Knee Adduction Moment | Knee Joint Loading (%Bw*Ht) | Change from baseline to 6 months after retraining |
| Serum inflammatory markers | Changes to serum inflammatory markers immediately after the end of training from baseline will be correlated with changes to joint loading | Change from baseline to immediately after 8 weeks of retraining |