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As the prevalence of motor impairment increases with age, the proportion of the population affected by physical limitations is likely to increase in the coming years, considering that one in three people will be over 60 in 2050 (compared to one in five in 2005, INSEE projections). The possibility of reducing recovery time and / or improving the improvement of motor deficits is today a public health issue. The possibility of developing new therapeutic tools using innovative motor imaging rehabilitation technologies is an opportunity to offer rehabilitation adapted to specific disorders, personalized in relation to the patient's performance, and in continuity with the therapist. In this research project, we will use the principle of neurofeedback rehabilitation (EEG) based on motor imaging with a brain-computer interface. Feedback will consist of therapeutic video games.Here, we will test the feasibility of such approach in 10 healthy subjects, 10 patients with amyotrophic lateral sclerosis and 10 patients with uppel shoulder surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Neurofeedback rehabilitation with videogames | Experimental | Neurofeedback rehabilitation with videogames |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Videogames | Device | Videogames |
|
| Measure | Description | Time Frame |
|---|---|---|
| Performance | total displacement fo the avatar within the game | week 1 |
| Measure | Description | Time Frame |
|---|---|---|
| electroencephalography activity | amplitude of the oscillatory activity | week 1, 2, 3, 4, 5 and 6 |
| functional brain MRI | BOLD signal | week 1 and 6 |
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Inclusion Criteria:
Common to the 3 populations concerned:
patients or subjects of both sexes;
age: 18-70 years;
ability to give consent in writing;
Health Insurance.
a) SLA:
patients with amyotrophic lateral sclerosis (defined according to the El Escorial criteria: possible, probable or definite), at the time of diagnosis;
Percentage of forced vital capacity (FVC) ≥ 65% of the predicted value for age, gender and size.
b) Patients after a shoulder trauma: patients with scheduled shoulder surgery. c) Healthy subjects.
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jean Christophe Corvol, MD, PHD | Contact | 01 42 16 57 72 | 0033 | jean-christophe.corvol@aphp.fr |
| Name | Affiliation | Role |
|---|---|---|
| Jean Christophe Corvol, MD, PHD | Groupe Hospitalier Pitié-Salpêtrière Paris, France, 75013 | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hopital PITIE SALPETRIERE | Recruiting | Paris | 75013 | France |
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