Open-label clinical study where all new patients presenting with cerebrovascular accidents and consenting to treatment are given intravenously a new combination of medications. Patients are evaluated neurologically with NIHSS scores before treatment administration and at 1 month after the first treatment. Further evaluations at 6 months after treatment by NIHSS and Barthel scores are ongoing

Patients with cerebrovascular accidents (CVA), ischemic (including those with hemorrhagic transformation), are given a new combination of medications which aims to improve neuronal survival, stimulate mitochondrial genesis and the formation of new synapses. This combination is given as an intravenous perfusion with a 2-hr duration and consists of vitamins B1, B6, B12, C, Actovegin, etc.

Before treatment a NIHSS score is given. Each patient receives 3-4 such perfusions in 1 month and afterwards another NIHSS score is obtained.

Patients are monitored afterwards and those who show improvements receive more such treatments, and new NIHSS and Barthel scores are obtained.

Patients are grouped on the basis of the time interval between CVA occurence and first treatment:

• Group 1: 0-35 days
• Group 2: 36-100 days
• Group 3: 101-360 days Improvement of motor function is compared using NIHSS scores between groups, and between literature and groups

Inclusion Criteria:

• adults with CVA
• agreeing to treatment in person or by proxy signing of Informed Consent Form
• available for NIHSS evaluation

Exclusion Criteria:

• allergy to any of the substances administered
• scheduled for surgery or other procedures
• not available for NIHSS evaluation after at least 48 hours from treatment