DMT310-001 Topical in the Treatment of Acne Vulgaris | NCT03536637 | Trialant

DMT310-001 Topical in the Treatment of Acne Vulgaris | NCT03536637 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Study Treatment 1	Experimental	DMT310 Powder mixed with Hydrogen Peroxide	Drug: DMT310 Drug: Hydrogen Peroxide
Study Treatment 2	Experimental	DMT310 Powder mixed with Placebo Diluent	Drug: DMT310
Study Treatment 3	Experimental	Placebo powder mixed with Hydrogen Peroxide	Drug: Hydrogen Peroxide Drug: Placebo
Control	Placebo Comparator	Placebo powder mixed with Placebo Diluent	Drug: Placebo

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Efficacy as measured by lesion counts	Inflammatory and Noninflammatory	12 weeks
Efficacy as measured by Investigator Global Assessment (IGA)	0 None No evidence of facial acne vulgaris Minimal Few noninflammatory lesions (comedones) are present; a few inflammatory lesions(papules/pustules) may be present; no nodulo-cystic lesions are allowed) Mild Several to many noninflammatory lesions (comedones) are present; a few inflammatory lesions (papules/pustules) are present; no nodulo-cystic lesions are allowed Moderate Many noninflammatory (comedones) and inflammatory lesions (papules/pustules) are present; no nodulo-cystic lesions are allowed Severe Significant degree of inflammatory disease; papules/pustules are a predominant feature; a few nodulo-cystic lesions may be present; comedones may be present	12 weeks

Contacts/Locations Module

Condition Browse Module