In this study the investigators aim to evaluate the ability of i-scan OE together with magnification endoscopy to detect and assess microscopic inflammation in patients with inflammator bowel diseases (IBD).

In this study the investigators aim to evaluate the ability of i-scan OE together with magnification endoscopy to detect and assess microscopic inflammation in patients with inflammator bowel diseases. For this purpose, IBD patients will be prospectively enrolled and inflammatory changes will be assessed using optical magnification endoscopy in conjunction with optical chromoendoscopy. Endoscopic scoring of inflammatory changes in IBD patients will be done on a newly developed magnification score resulting as a consensus from experts in optical diagnosis and endoscopy in IBD patients. Results will be correlated against histopathology.

Inclusion Criteria:

• Patients with established diagnosis of Inflammatory Bowel Diseases
• Ability to provide written informed consent
• Age 18 years and older

Exclusion Criteria:

• poor bowel preparation
• inability to provide written informed consent
• minors

IBD patients treated in the outpatient department of the University Hospital Erlangen