Work of Breathing and Oxygen Saturation in Infants Receiving High Flow Nasal Cannula (HFNC)

Work of Breathing and Oxygen Saturation Stability in Infants With Respiratory Insufficiency While Receiving Various Flow Rates of High Flow Nasal Cannula

The purpose of this study is to compare work of breathing on different levels of high flow respiratory support on infants born between 27 and 37 weeks gestation.

Inclusion Criteria:

• Infants between 27 and 37 weeks corrected gestational age
• >4 days PNA
• Stable (i.e. not meeting exclusion criteria) and receiving non-invasive respiratory support (HFNC) for ≥ 12 hours
• Requiring ≤ 40% supplemental FiO2 as determined by the clinical care team for clinical care purposes independent of this study

Exclusion Criteria:

• Infants with skeletal, neuromuscular, or abdominal surgical disorders that affect the accuracy of WOB measurements